Urdme: a modular framework for stochastic simulation of reaction-transport processes in complex geometries. We have developed URDME, a flexible software framework for general stochastic reaction-transport modeling and simulation. URDME uses Unstructured triangular and tetrahedral meshes to resolve general geometries, and relies on the Reaction-Diffusion Master Equation formalism to model the processes under study. An interface to a mature geometry and mesh handling external software (Comsol Multiphysics) provides for a stable and interactive environment for model construction. The core simulation routines are logically separated from the model building interface and written in a low-level language for computational efficiency. The connection to the geometry handling software is realized via a Matlab interface which facilitates script computing, data management, and post-processing. For practitioners, the software therefore behaves much as an interactive Matlab toolbox. At the same time, it is possible to modify and extend URDME with newly developed simulation routines. Since the overall design effectively hides the complexity of managing the geometry and meshes, this means that newly developed methods may be tested in a realistic setting already at an early stage of development.

References in zbMATH (referenced in 9 articles )

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  1. Blanc, Emilie; Engblom, Stefan; Hellander, Andreas; Lötstedt, Per: Mesoscopic modeling of stochastic reaction-diffusion kinetics in the subdiffusive regime (2016)
  2. Drawert, Brian; Trogdon, Michael; Toor, Salman; Petzold, Linda; Hellander, Andreas: MOLNs: a cloud platform for interactive, reproducible, and scalable spatial stochastic computational experiments in systems biology using pyurdme (2016)
  3. Meinecke, Lina; Lötstedt, Per: Stochastic diffusion processes on Cartesian meshes (2016)
  4. Agbanusi, I.C.; Isaacson, S.A.: A comparison of bimolecular reaction models for stochastic reaction-diffusion systems (2014)
  5. Erban, Radek (ed.); Othmer, Hans G. (ed.): Editorial: Special issue on stochastic modelling of reaction-diffusion processes in biology (2014)
  6. Hellander, Andreas; Lawson, Michael J.; Drawert, Brian; Petzold, Linda: Local error estimates for adaptive simulation of the reaction-diffusion master equation via operator splitting (2014)
  7. Sturrock, Marc; Hellander, Andreas; Aldakheel, Sahar; Petzold, Linda; Chaplain, Mark A.J.: The role of dimerisation and nuclear transport in the Hes1 gene regulatory network (2014)
  8. Wang, Siyang; Elf, Johan; Hellander, Stefan; Lötstedt, Per: Stochastic reaction-diffusion processes with embedded lower-dimensional structures (2014)
  9. Engblom, Stefan; Ferm, Lars; Hellander, Andreas; Lötstedt, Per: Simulation of stochastic reaction-diffusion processes on unstructured meshes (2009)