PROSPINO: A Program for the Production of Supersymmetric Particles in Next-to-leading Order QCD. A Fortran-program for the production cross-sections of squarks and gluinos at hadron colliders is described. It includes full next-to-leading order SUSY-QCD corrections to all possible final states ($squarksquarkbar, gluinogluino, squarkgluino, squarksquark$). The program allows to calculate total cross-sections as well as differential distributions in the transverse momentum p_t and the rapidity y of one of the outgoing particles. In addition cuts in p_t and y can easily be implemented.