Biodoop: bioinformatics on hadoop. Biodoop is a suite of tools for computational biology that focuses on the efficient, distributed implementation of the most computationally demanding and/or data-intensive tasks. It consists of a core component, which includes a set of general-purpose modules, plus a number of application-specific components. Current applications focus on sequence alignment and manipulation of alignment records. Applications generally run on the Pydoop API for Hadoop and are built to scale well in both the number of computing nodes available and the amount of data to process, making them particularly well suited for processing large data sets.