IGV-plus: a Java software for the analysis and visualization of next-generation sequencing data. In this work we describe IGV-{it plus}, a software for next-generation sequencing (NGS) data analysis and visualization. It integrates de facto standard tools for the discovery of genetic mutations in genomic-wide association studies. We describe the software specification that led to the development of IGV-{it plus}. Finally, we show how we integrate a single-nucleotide polymorphism (SNP) calling software of the genome analysis toolkit (GATK) in the genome browser integrative genomics viewer (IGV), in order to create a centralized platform, as a possible one-stop shop for biologists dealing with NGS data.