TMAC: A Toolbox of Modern Async-Parallel, Coordinate, Splitting, and Stochastic Methods. TMAC is a toolbox written in C++11 that implements algorithms based on a set of modern methods for large-scale optimization. It covers a variety of optimization problems, which can be both smooth and nonsmooth, convex and nonconvex, as well as constrained and unconstrained. The algorithms implemented in TMAC, such as the coordinate up- date method and operator splitting method, are scalable as they decompose a problem into simple subproblems. These algorithms can run in a multi-threaded fashion, either synchronously or asynchronously, to take advantages of all the cores available. TMAC architecture mimics how a scientist writes down an optimization algorithm. Therefore, it is easy for one to obtain a new algorithm by making simple modifications such as adding a new operator and adding a new splitting, while maintaining the multicore parallelism and other features. The package is available at this https URL