R package ICAOD. Finding locally D-optimal, minimax D-optimal, standardized maximin D-optimal, optim-on-the-average and multiple objective optimal designs for nonlinear models. Different Fisher information matrices can also be set by user. There are also useful functions for verifying the optimality of the designs with respect to different criteria by equivalence theorem. ICA is a meta-heuristic evolutionary algorithm inspired from the socio-political process of humans. See Masoudi et al. (2016) &lt;<a href=”http://dx.doi.org/10.1016/j.csda.2016.06.014”>doi:10.1016/j.csda.2016.06.014</a>&gt;.

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  1. Antony Overstall, David Woods, Maria Adamou: acebayes: An R Package for Bayesian Optimal Design of Experiments via Approximate Coordinate Exchange (2017) arXiv