R package trioGxE: A data smoothing approach to explore and test gene-environment interaction in case-parent trio data. The package contains functions that 1) estimates gene-environment interaction between a SNP and a continuous non-genetic attribute by fitting a generalized additive model to case-parent trio data, 2) produces graphical displays of estimated interaction, 3) performs permutation test of gene-environment interaction; 4) simulates informative case-parent trios.
Keywords for this software
References in zbMATH (referenced in 2 articles , 1 standard article )
Showing results 1 to 2 of 2.
- Shin, Ji-Hyung; Infante-Rivard, Claire; McNeney, Brad; Graham, Jinko: A data-smoothing approach to explore and test gene-environment interaction in case-parent trios (2014)
- Shin, Ji-Hyung; Infante-Rivard, Claire; Graham, Jinko; McNeney, Brad: Adjusting for spurious gene-by-environment interaction using case-parent triads (2012)