PFIM : population design evaluation and optimisation. PFIM (Population Fisher Information Matrix) is a R function dedicated to evaluation and optimisation of designs (number of subjects, number of samples per subject and their allocation in time) for nonlinear mixed effects models (population approach). This function is based on the developpement of an approximation of the Fisher information matrix in these model

Keywords for this software

Anything in here will be replaced on browsers that support the canvas element