TETRASAT: a program for the population analysis of allotetraploid microsatellite data. TETRASAT (Markwith et al., 2006) was written for the purpose of calculating genetic diversity, HE, and H’, and population differentiation, GST, statistics for populations of allotetraploid species that have been analyzed using mircosatellite markers. Due to the exponential amplification process, allele copy number can not be determined for partial heterozygote individuals, thus existing methods of calculating these statistics are largely inadequate. TETRSAT uses an iterative substitution process to determine all possible combinations of genotypes and allele frequencies for each population, and calculates the subsequently calculates the necessary statistics. More information concerning the impetus behind the development of TETRASAT, the logic behind its operation, and its utility can be found in Markwith et al. (2006)

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  1. Sherwin, William B.: Entropy and information approaches to genetic diversity and its expression: genomic geography (2010)