MetaCyc is a database of nonredundant, experimentally elucidated metabolic pathways. MetaCyc contains more than 2097 pathways from more than 2460 different organisms and is curated from the scientific experimental literature. MetaCyc contains pathways involved in both primary and secondary metabolism, as well as associated compounds, enzymes, and genes The goal of MetaCyc is to catalog the universe of metabolism by storing a representative sample of each experimentally elucidated pathway. MetaCyc is used in a variety of scientific applications, such as providing a reference data set for computationally predicting the metabolic pathways of organisms from their sequenced genomes, supporting metabolic engineering, helping to compare biochemical networks, and serving as an encyclopedia of metabolism.

References in zbMATH (referenced in 11 articles )

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  1. Pinter, Ron Y.; Zehavi, Meirav: Algorithms for topology-free and alignment network queries (2014)
  2. Desai, Dhwani K.; Nandi, Soumyadeep; Srivastava, Prashant K.; Lynn, Andrew M.: ModEnzA: accurate identification of metabolic enzymes using function specific profile HMMs with optimised discrimination threshold and modified emission probabilities (2011)
  3. Stingo, Francesco C.; Chen, Yian A.; Tadesse, Mahlet G.; Vannucci, Marina: Incorporating biological information into linear models: a Bayesian approach to the selection of pathways and genes (2011)
  4. Baldan, Paolo; Cocco, Nicoletta; Marin, Andrea; Simeoni, Marta: Petri nets for modelling metabolic pathways: a survey (2010)
  5. Chen, Chuming; McGarvey, Peter B.; Huang, Hongzhan; Wu, Cathy H.: Protein bioinformatics infrastructure for the integration and analysis of multiple high-throughput “omics” data (2010)
  6. Likić, Vladimir A.; Mcconville, Malcolm J.; Lithgow, Trevor; Bacic, Antony: Systems biology: the next frontier for bioinformatics (2010)
  7. Chou, I-Chun; Voit, Eberhard O.: Recent developments in parameter estimation and structure identification of biochemical and genomic systems (2009)
  8. Félix, Liliana; Rosselló, Francesc; Valiente, Gabriel: Efficient reconstruction of metabolic pathways by bidirectional chemical search (2009)
  9. Heath, Allison P.; Kavraki, Lydia E.: Computational challenges in systems biology (2009)
  10. Tran, Nam; Baral, Chitta: Hypothesizing about signaling networks (2009)
  11. Xu, Ying: Computational challenges in deciphering genomic structures of bacteria (2009)