BooleSim: an interactive Boolean network simulator. SUMMARY: BooleSim (Boolean network simulator) is an open-source in-browser tool for simulation and manipulation of Boolean networks. It was developed mainly during Google’s Summer of Code 2012 and uses the biographer project for network visualization. It can be used specifically for the modeling of gene regulatory or signal transduction networks. AVAILABILITY AND IMPLEMENTATION: BooleSim is free software and can be downloaded from GitHub ( Online version available at

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