STRAP: Interactive Structure based Sequences Alignment Program. The free computer program Strap aligns proteins by sequence and 3D-structure und Windows, Macintosh, Linux and Unix. Run the demo showing 6 sequences of the proteasome within a secure Strap session. Strap supports the simultaneous analysis of hundreds of proteins and integrates amino acid sequence, secondary structure, 3D-structure and genomic- and mRNA-sequence and residue annotation. Snapshot of the Strap application. Bottom panel: Multiple sequence alignment in Strap. Four proteins are selected and conserved amino acids are colorized according to chemical property. Top panel: One of the proteins is shown in 3D. screenshot The alignment can be exported and modified in MS-Word or other text processors. Import and export of proteins is very easy by WIKI:Drag-and-Drop. The included tutorial will teach the use of Strap in as little as one hour. The scriptability and extendability make Strap a very powerful tool for even the most advanced users. The software programmed in Java and runs on all platforms. It will be permanently improved.

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  1. Keith, Jonathan M. (ed.): Bioinformatics. Volume I. Data, sequence analysis, and evolution (2017)
  2. Gunther, Stefan; Senger, Christian; Michalsky, Elke; Goede, Andrean; Preissner, Robert: Representation of target-bound drugs by computed conformers: Implications for conformational libraries (2006) ioport