UniProt

UniProt: a hub for protein information. UniProt is an important collection of protein sequences and their annotations, which has doubled in size to 80 million sequences during the past year. This growth in sequences has prompted an extension of UniProt accession number space from 6 to 10 characters. An increasing fraction of new sequences are identical to a sequence that already exists in the database with the majority of sequences coming from genome sequencing projects. We have created a new proteome identifier that uniquely identifies a particular assembly of a species and strain or subspecies to help users track the provenance of sequences. We present a new website that has been designed using a user-experience design process. We have introduced an annotation score for all entries in UniProt to represent the relative amount of knowledge known about each protein. These scores will be helpful in identifying which proteins are the best characterized and most informative for comparative analysis. All UniProt data is provided freely and is available on the web at http://www.uniprot.org/.


References in zbMATH (referenced in 136 articles , 1 standard article )

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  1. Tobi, Dror; Bahar, Ivet: Recruitment of rare 3-grams at functional sites: Is this a mechanism for increasing enzyme specificity? (2007) ioport
  2. Deng, Xutao; Geng, Huimin; Bastola, Dhundy R.; Ali, Hesham H.: Link test -- a statistical method for finding prostate cancer biomarkers (2006)
  3. Jithesh, P. V.; Donachy, P.; Harmer, T.; Kelly, N.; Perrott, R.; Wasnik, S.; Johnston, J.; McCurley, M.; Townsley, M.; McKee, S.: GeneGrid: Architecture, implementation and application (2006)
  4. Jithesh, P. V.; Donachy, P.; Harmer, T.; Kelly, N.; Perrott, R.; Wasnik, S.; Johnston, J.; McCurley, M.; Townsley, M.; McKee, S.: GeneGrid: Architecture, implementation and application (2006) ioport
  5. Li, Minghui; Wang, Xiaolong; Lin, Lei; Liu, Tao: Effect of example weights on prediction of protein-protein interactions (2006)
  6. Portugaly, Elon; Harel, Amir; Linial, Nathan; Linial, Michal: EVEREST: Automatic identification and classification of protein domains in all protein sequences (2006) ioport
  7. Roy, Sourav; Schnell, Santiago; Radivojac, Predrag: Unraveling the nature of the segmentation clock: Intrinsic disorder of clock proteins and their interaction map (2006)
  8. Wu, Cathy H.; Apweiler, Rolf; Bairoch, Amos; Natale, Darren A.; Barker, Winona C.; Boeckmann, Brigitte; Ferro, Serenella; Gasteiger, Elisabeth; Huang, Hongzhan; Lopez, Rodrigo; Magrane, Michele; Martin, Maria Jesus; Mazumder, Raja; O’donovan, Claire; Redaschi, Nicole; Suzek, Baris E.: The universal protein resource (UniProt): An expanding universe of protein information. (2006) ioport
  9. Bairoch, Amos; Apweiler, Rolf; Wu, Cathy H.; Barker, Winona C.; Boeckmann, Brigitte; Ferro, Serenella; Gasteiger, Elisabeth; Huang, Hongzhan; Lopez, Rodrigo; Magrane, Michele; Martín, María J.; Natale, Darren A.; O’donovan, Claire; Redaschi, Nicole; Yeh, Lai-Su L.: The universal protein resource (UniProt). (2005) ioport
  10. Bhagwat, Deepavali; Chiticariu, Laura; Tan, Wang-Chiew; Vijayvargiya, Gaurav: An annotation management system for relational databases (2005) ioport
  11. Claypool, Kajal T.; Rundensteiner, Elke A.: TAX: a tree algebra for XML (2005) ioport
  12. Liu, Yan; Carbonell, Jaime; Weigele, Peter; Gopalakrishnan, Vanathi: Segmentation conditional random fields (SCRFs): A new approach for protein fold recognition (2005)
  13. Tian, Yuanyuan; Tata, Sandeep; Hankins, Richard A.; Patel, Jignesh M.: Algorithms for parallel memory: Two-level memories (2005) ioport
  14. Apweiler, Rolf; Bairoch, Amos; Wu, Cathy H.; Barker, Winona C.; Boeckmann, Brigitte; Ferro, Serenella; Gasteiger, Elisabeth; Huang, Hongzhan; Lopez, Rodrigo; Magrane, Michele; Martin, Maria Jesus; Natale, Darren A.; O’donovan, Claire; Redaschi, Nicole; Yeh, Lai-Su L.: Uniprot: The universal protein knowledgebase. (2004) ioport
  15. Hu, Zhang-Zhi; Mani, Inderjeet; Hermoso, Vincent; Liu, Hongfang; Wu, Cathy H.: iProLINK: an integrated protein resource for literature mining (2004)
  16. Wu, Cathy H.; Huang, Hongzhan; Nikolskaya, Anastasia; Hu, Zhangzhi; Barker, Winona C.: The iProClass integrated database for protein functional analysis (2004)

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