qvalue
R package qvalue: Q-value estimation for false discovery rate control. This package takes a list of p-values resulting from the simultaneous testing of many hypotheses and estimates their q-values and local FDR values. The q-value of a test measures the proportion of false positives incurred (called the false discovery rate) when that particular test is called significant. The local FDR measures the posterior probability the null hypothesis is true given the test’s p-value. Various plots are automatically generated, allowing one to make sensible significance cut-offs. Several mathematical results have recently been shown on the conservative accuracy of the estimated q-values from this software. The software can be applied to problems in genomics, brain imaging, astrophysics, and data mining.
Keywords for this software
References in zbMATH (referenced in 8 articles )
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Sorted by year (- McKennan, Chris; Ober, Carole; Nicolae, Dan: Estimation and inference in metabolomics with nonrandom missing data and latent factors (2020)
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- Zhang, Fang; Shan, Ang; Luan, Yihui: A novel method to accurately calculate statistical significance of local similarity analysis for high-throughput time series (2018)
- Habiger, Joshua D.: Multiple test functions and adjusted (p)-values for test statistics with discrete distributions (2015)
- Shim, Heejung; Stephens, Matthew: Wavelet-based genetic association analysis of functional phenotypes arising from high-throughput sequencing assays (2015)
- Kris Sankaran; Susan Holmes: structSSI: Simultaneous and Selective Inference for Grouped or Hierarchically Structured Data (2014) not zbMATH
- Hackstadt, Amber J.; Hess, Ann M.: Filtering for increased power for microarray data analysis (2009) ioport
- Dudoit, Sandrine; Gilbert, Houston N.; van der Laan, Mark J.: Resampling-based empirical Bayes multiple testing procedures for controlling generalized tail probability and expected value error rates: focus on the false discovery rate and simulation study (2008)