MulRF is a platform-independent software program designed to infer species trees from incongruent multi-copy gene trees using a generalization of the Robinson-Foulds (RF) distance to multi-labeled trees. MulRF version 1.2 has following additional features: Weighted input gene trees for species tree search. Topological constraints on the inferred species tree. Automated execution of multiple replicates of tree search heuristic. MulRF distance of a given species tree from gene trees. Visualization of input/output trees. MulRF’s source code is availabel at