Hybrid Bidiagonalization Regularization (HyBR). Hybrid regularization methods have been proposed as effective approaches for solving large-scale ill-posed inverse problems. These methods restrict the solution to lie in a Krylov subspace, but they are hindered by semi-convergence behavior, in that the quality of the solution first increases and then decreases. Hybrid methods apply a standard regularization technique, such as Tikhonov regularization, to the projected problem at each iteration. Thus, regularization in hybrid methods is achieved both by Krylov filtering and by appropriate choice of a regularization parameter at each iteration.