CREx: inferring genomic rearrangements based on common intervals. : We present the web-based program CREx for heuristically determining pairwise rearrangement events in unichromosomal genomes. CREx considers transpositions, reverse transpositions, reversals and tandem-duplication-random-loss (TDRL) events. It supports the user in finding parsimonious rearrangement scenarios given a phylogenetic hypothesis. CREx is based on common intervals, which reflect genes that appear consecutively in several of the input gene orders. Availability: CREx is freely available at

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References in zbMATH (referenced in 4 articles )

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  1. Hellmuth, Marc; Hernandez-Rosales, Maribel; Long, Yangjing; Stadler, Peter F.: Inferring phylogenetic trees from the knowledge of rare evolutionary events (2018)
  2. Pelletier, Léo; Rusu, Irena: Common intervals and permutation reconstruction from \textitMinMax-betweenness constraints (2018)
  3. Rusu, Irena: New applications of interval generators to genome comparison (2012)
  4. Bernt, Matthias; Merkle, Daniel; Ramsch, Kai; Fritzsch, Guido; Perseke, Marleen; Bernhard, Detlef; Schlegel, Martin; Stadler, Peter F.; Middendorf, Martin: Crex: Inferring genomic rearrangements based on common intervals (2007) ioport