Bioconductor/R package SomaticSignatures: Somatic Signatures - The SomaticSignatures package identifies mutational signatures of single nucleotide variants (SNVs). It provides a infrastructure related to the methodology described in Nik-Zainal (2012, Cell), with flexibility in the matrix decomposition algorithms.

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  1. Robinson, Peter N.; Piro, Rosario Michael; J├Ąger, Marten: Computational exome and genome analysis (2018)