R package SubgrpID: Patient Subgroup Identification for Clinical Drug Development. Function Wrapper contains four algorithms for developing threshold-based multivariate (prognostic/predictive) biomarker signatures via bootstrapping and aggregating of thresholds from trees, Monte-Carlo variations of the Adaptive Indexing method and Patient Rule Induction Method. Variable selection is automatically built-in to these algorithms. Final signatures are returned with interaction plots for predictive signatures. Cross-validation performance evaluation and testing dataset results are also output.

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  1. Jared D. Huling, Menggang Yu: Subgroup Identification Using the personalized Package (2021) not zbMATH